| Active ingredient | Permethrin 50 mg per 1 g of lotion (5%) |
|---|---|
| Form | White, non-greasy scabicidal lotion |
| Pack sizes | 50 ml (one to two applications) and 100 ml (two to three applications) |
| Scheduling status | S0 available without a prescription |
| Registration number | A40/13.2/0756 |
| NAPPI code | 713148-001 |
| Barcode | 6009665060002 |
| Classification | A 13.12 Dermatological preparations, other |
What it is for
Skabi-Rid is indicated for the treatment of infestations with Sarcoptes scabiei (scabies).
How it works
Permethrin is a pyrethroid. It acts on the nerve cell membrane of the mite, disrupting the sodium channels that control the membrane's polarisation. This paralyses and kills the mite.
Permethrin is a synthetic relative of the pyrethrins, natural insecticides from the chrysanthemum plant. Chrysanthemums were grown in China as far back as the 15th century BC, and about 200 years ago people in central Asia discovered that dried, crushed flowers of certain chrysanthemums were toxic to insects. Permethrin is designed to stay stable in ultraviolet light while keeping that potent effect.
Why permethrin 5%
- Recommended as first-line treatment for scabies in guidelines worldwide, and in the South African Standard Treatment Guidelines and Essential Medicines List for primary health care.
- Listed on the WHO Model List of Essential Medicines.
- One application, left on overnight. The package insert says to repeat after two weeks if necessary.
Skabi-Rid was the first permethrin-only scabicide in South Africa. Its formulation was developed by the Research Institute for Industrial Pharmacy in Potchefstroom and tested in a randomised South African clinical trial.
How to use it
Shake the bottle. Apply over the whole body from the ears all the way down to the soles of the feet. Leave on overnight and wash off the following morning, after eight to twelve hours. Do not apply directly to the face. See the step-by-step guide.
Warnings and side effects
- Do not use if you are sensitive to permethrin or any of the other ingredients.
- Stop using it if you become hypersensitive to Skabi-Rid. Avoid contact with the eyes. For external use only.
- Burning of the skin has been reported, less often. Itching, stinging and redness are rare.
- The safety of this preparation in pregnancy and breastfeeding has not been established. Speak to your doctor or pharmacist first.
- If accidentally swallowed, get medical help.
Storage
Store below 25 °C in a cool place. Keep out of reach of children. Do not use after the expiry date on the label.
S0 Skabi-Rid is a registered medicine (Reg. No. A40/13.2/0756). Read the package insert before use. If symptoms persist, see your doctor or pharmacist.